Recently, the review article “Silver-Catalyzed Activation of Terminal Alkynes for Synthesizing Nitrogen-Containing Molecules” written by Professor Bi Xihe’s research group in the school of chemistry in NENU has been published in Accounts of Chemical Research, the important international scientific journals commonly recognized by academic circle. The review article systematically introduced the research achievements of research group on Silver-Catalyzed Activation of Terminal Alkynes. The first author of this review is Dr. Paramasivam Sivaguru, and Bi Xihe is the corresponding author.
Transition metal catalysis has promoted the rapid development of modern organic chemistry. The outer electrons of each metal are different, and the ability to gain and lose electrons is also very different, resulting in the diversity and uniqueness of catalysis. Therefore, it is of great significance to study a specific transition metal, to reveal the catalytic mechanism, and to establish a unique catalytic reaction system. Silver catalytic chemistry has a long history of research, but compared with other extensively studied transition metals, the development of silver-catalyzed organic reactions is relatively slow, and the knowledge structure is unsystematically, and the catalytic potential needs to be explored urgently. In the past ten years, Bi Xihe and his research group have carried out systematic research work in the field of silver-catalyzed organic reactions. Based on the structural characteristics and experimental findings of silver valence shells, they have summarized the proton-like properties and reversible activation of silver, and developed silver σ-Activated alkyne new strategy, established a series of silver-catalyzed activation of alkyne series organic reactions, developed a new method for the synthesis of nitrogen-containing organic molecules, and clarified the mechanism of the reaction. These research results not only developed a series of novel organic reactions with the uniqueness of silver catalysis, but also explored its catalytic nature from a theoretical level, forming a new cognition. This review article has guiding significance for understanding the theory of silver catalysis and developing silver-catalyzed organic reactions.
The journal Accounts of Chemical Research has great influence in the fields of chemistry and chemical engineering and materials science, and the content mainly contains reviewing author’s own systematic research. These research work has been funded by the National Natural Science Foundation, Jilin Science and Technology Department and National University Scientific Research Operating Expenses.
(From News Center, translated by Zhang Wanying, revised by Chen Yanxu)