NENU has made new progress in research on organic synthesis. The thesis paper "Domino Ring-Openin/Recyclization Reactions of Doubly Activated Cyclopropanes as a Strategy for the Synthesis of Furoquinoline Derivatives" written by Professor Liu Qun and Associate Professor Zhang Qian was published in Applied Chemistry, a German academic magazine. In this communication, a new strategy for the synthesis of furoquinoline derivatives through a novel SnCl4-mediated tandem ring-opening/recyclization reaction of the doubly activated cyclopropanes (doubly activated cyclopropane→furan→furoquinoline) was developed. Providing theoretical guidance, this new strategy, with high chemo- and regioselectivity, high efficiency, operational simplicity, and the ready availability of wide range of substrates from cheap raw materials, will be widely applied in the future. This breakthrough is one of the achievements recently gained under the policies of boosting investment in basic research and strengthening independent innovation. It indicated that some of NENU's basic research programs already became top-ranking in their respective fields of research in the world. Further studies on it are being conducted and it is expected that a series of innovative results will be released soon.
(From School of Chemistry & Social Science Management, translated by Zhang Qian, Qian Shunan, revised by Jiang Yansheng)
